Hypoxia-induced autophagy is inhibited by PADI4 knockdown, which promotes apoptosis of fibroblast-like synoviocytes in rheumatoid arthritis

Impaired apoptosis of rheumatoid arthritis (RA)-fibroblast-like synoviocytes (FLS) is pivotal in the process of RA. Peptidyl arginine deiminase type IV (PADI4) is associated with autoantibody regulation via histone citrullination in RA. The present study aimed to investigate the role of PADI4 in the...

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Detalles Bibliográficos
Autores principales: Fan, Tingting, Zhang, Changsong, Zong, Ming, Fan, Lieying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865976/
https://www.ncbi.nlm.nih.gov/pubmed/29393388
http://dx.doi.org/10.3892/mmr.2018.8501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865976/
https://www.ncbi.nlm.nih.gov/pubmed/29393388
http://dx.doi.org/10.3892/mmr.2018.8501

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