High glucose induces podocyte epithelial-to-mesenchymal transition by demethylation-mediated enhancement of MMP9 expression

Abnormal expression of matrix metalloproteinase 9 (MMP9) is correlated with podocyte epithelial-to-mesenchymal transition (EMT) in diabetic nephropathy (DN). However, the mechanisms underlying this process are not well defined. Site-specific demethylation may sustain high expression levels of target...

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Detalles Bibliográficos
Autores principales: Ling, Li, Chen, Libo, Zhang, Changning, Gui, Shuyan, Zhao, Haiyan, Li, Zhengzhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866005/
https://www.ncbi.nlm.nih.gov/pubmed/29436620
http://dx.doi.org/10.3892/mmr.2018.8554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866005/
https://www.ncbi.nlm.nih.gov/pubmed/29436620
http://dx.doi.org/10.3892/mmr.2018.8554

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