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High glucose induces podocyte epithelial-to-mesenchymal transition by demethylation-mediated enhancement of MMP9 expression
Abnormal expression of matrix metalloproteinase 9 (MMP9) is correlated with podocyte epithelial-to-mesenchymal transition (EMT) in diabetic nephropathy (DN). However, the mechanisms underlying this process are not well defined. Site-specific demethylation may sustain high expression levels of target...
Autores principales: | Ling, Li, Chen, Libo, Zhang, Changning, Gui, Shuyan, Zhao, Haiyan, Li, Zhengzhang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866005/ https://www.ncbi.nlm.nih.gov/pubmed/29436620 http://dx.doi.org/10.3892/mmr.2018.8554 |
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