Interleukin-10 promotes primary rat hepatic stellate cell senescence by upregulating the expression levels of p53 and p21

Liver fibrosis is characterized by the excessive deposition of extracellular matrix (ECM) components, and activated hepatic stellate cells (HSCs) are a primary source of ECM. Several studies have revealed that the induction of HSC senescence may reduce liver fibrosis. The effect of interleukin-10 (I...

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Detalles Bibliográficos
Autores principales: Huang, Yue-Hong, Chen, Ming-Hua, Guo, Qi-Lan, Chen, Yun-Xin, Zhang, Li-Juan, Chen, Zhi-Xin, Wang, Xiao-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866012/
https://www.ncbi.nlm.nih.gov/pubmed/29436649
http://dx.doi.org/10.3892/mmr.2018.8592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866012/
https://www.ncbi.nlm.nih.gov/pubmed/29436649
http://dx.doi.org/10.3892/mmr.2018.8592

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