Hypothyroidism increases cyclooxygenase-2 levels and pro-inflammatory response and decreases cell proliferation and neuroblast differentiation in the hippocampus

The present study investigated the effects of hypothyroidism on cyclooxygenase-2 (COX-2) and pro-inflammatory cytokines in the dentate gyrus to elucidate the roles of COX-2 in the hypothyroid hippocampus. Hypothyroidism was induced in rats by treating with 0.03% 2-mercapto-1-methyl-imidazole dissolv...

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Detalles Bibliográficos
Autores principales: Nam, Sung Min, Kim, Jong Whi, Yoo, Dae Young, Jung, Hyo Young, Chung, Jin Young, Kim, Dae Won, Hwang, In Koo, Yoon, Yeo Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866021/
https://www.ncbi.nlm.nih.gov/pubmed/29436670
http://dx.doi.org/10.3892/mmr.2018.8605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866021/
https://www.ncbi.nlm.nih.gov/pubmed/29436670
http://dx.doi.org/10.3892/mmr.2018.8605

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