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Hypoxia Inducible Factor 1α Plays a Key Role in Remote Ischemic Preconditioning Against Stroke by Modulating Inflammatory Responses in Rats

BACKGROUND: Limb remote ischemic preconditioning (RIPC) protects against brain injury induced by stroke, but the underlying protective mechanisms remain unknown. As hypoxia inducible factor 1α (HIF‐1α) is neuroprotective in stroke and mediates neuroinflammation, we tested the hypothesis that HIF‐1α...

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Detalles Bibliográficos
Autores principales: Yang, Jian, Liu, Cuiying, Du, Xiangnan, Liu, Menglei, Ji, Xunming, Du, Huishan, Zhao, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866324/
https://www.ncbi.nlm.nih.gov/pubmed/29478025
http://dx.doi.org/10.1161/JAHA.117.007589