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Activation of the sweet taste receptor, T1R3, by the artificial sweetener sucralose regulates the pulmonary endothelium

A hallmark of acute respiratory distress syndrome (ARDS) is pulmonary vascular permeability. In these settings, loss of barrier integrity is mediated by cell-contact disassembly and actin remodeling. Studies into molecular mechanisms responsible for improving microvascular barrier function are there...

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Detalles Bibliográficos
Autores principales: Harrington, Elizabeth O., Vang, Alexander, Braza, Julie, Shil, Aparna, Chichger, Havovi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866431/
https://www.ncbi.nlm.nih.gov/pubmed/28971978
http://dx.doi.org/10.1152/ajplung.00490.2016