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Enhanced interlaminar excitation or reduced superficial layer inhibition in neocortex generates different spike-and-wave-like electrographic events in vitro

Acute in vitro models have revealed a great deal of information about mechanisms underlying many types of epileptiform activity. However, few examples exist that shed light on spike-and-wave (SpW) patterns of pathological activity. SpW are seen in many epilepsy syndromes, both generalized and focal,...

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Detalles Bibliográficos
Autores principales: Hall, Stephen P., Traub, Roger D., Adams, Natalie E., Cunningham, Mark O., Schofield, Ian, Jenkins, Alistair J., Whittington, Miles A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866469/
https://www.ncbi.nlm.nih.gov/pubmed/28954894
http://dx.doi.org/10.1152/jn.00516.2017