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Enhanced interlaminar excitation or reduced superficial layer inhibition in neocortex generates different spike-and-wave-like electrographic events in vitro
Acute in vitro models have revealed a great deal of information about mechanisms underlying many types of epileptiform activity. However, few examples exist that shed light on spike-and-wave (SpW) patterns of pathological activity. SpW are seen in many epilepsy syndromes, both generalized and focal,...
Autores principales: | Hall, Stephen P., Traub, Roger D., Adams, Natalie E., Cunningham, Mark O., Schofield, Ian, Jenkins, Alistair J., Whittington, Miles A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866469/ https://www.ncbi.nlm.nih.gov/pubmed/28954894 http://dx.doi.org/10.1152/jn.00516.2017 |
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