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Distinct metabolic programs induced by TGF-β1 and BMP2 in human articular chondrocytes with osteoarthritis

OBJECTIVES: Cellular energy metabolism is important for the function of all tissues, including cartilage. Recent studies indicate that superficial and deep subpopulations of articular chondrocytes (ACs) have distinct metabolic profiles. At the cellular and molecular level, osteoarthritis (OA) is cha...

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Detalles Bibliográficos
Autores principales: Wang, Cuicui, Silverman, Richard M., Shen, Jie, O'Keefe, Regis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866480/
https://www.ncbi.nlm.nih.gov/pubmed/29662780
http://dx.doi.org/10.1016/j.jot.2017.12.004