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Atrophy of the putamen at time of clinical motor onset in Huntington’s disease: a 6-year follow-up study

BACKGROUND: Striatal atrophy is detectable many years before the predicted onset of motor symptoms in premanifest Huntington’s disease (HD). However, the extent of these neurodegenerative changes at the actual time of conversion from premanifest to a motor manifest disease stage is not known. With t...

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Detalles Bibliográficos
Autores principales: Coppen, Emma M., van der Grond, Jeroen, Roos, Raymund A. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866517/
https://www.ncbi.nlm.nih.gov/pubmed/29593880
http://dx.doi.org/10.1186/s40734-018-0069-3