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Atrophy of the putamen at time of clinical motor onset in Huntington’s disease: a 6-year follow-up study
BACKGROUND: Striatal atrophy is detectable many years before the predicted onset of motor symptoms in premanifest Huntington’s disease (HD). However, the extent of these neurodegenerative changes at the actual time of conversion from premanifest to a motor manifest disease stage is not known. With t...
Autores principales: | Coppen, Emma M., van der Grond, Jeroen, Roos, Raymund A. C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866517/ https://www.ncbi.nlm.nih.gov/pubmed/29593880 http://dx.doi.org/10.1186/s40734-018-0069-3 |
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