Foxp1 controls mature B cell survival and the development of follicular and B-1 B cells

The transcription factor Foxp1 is critical for early B cell development. Despite frequent deregulation of Foxp1 in B cell lymphoma, the physiological functions of Foxp1 in mature B cells remain unknown. Here, we used conditional gene targeting in the B cell lineage and report that Foxp1 disruption i...

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Detalles Bibliográficos
Autores principales: Patzelt, Thomas, Keppler, Selina J., Gorka, Oliver, Thoene, Silvia, Wartewig, Tim, Reth, Michael, Förster, Irmgard, Lang, Roland, Buchner, Maike, Ruland, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866538/
https://www.ncbi.nlm.nih.gov/pubmed/29507226
http://dx.doi.org/10.1073/pnas.1711335115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866538/
https://www.ncbi.nlm.nih.gov/pubmed/29507226
http://dx.doi.org/10.1073/pnas.1711335115

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