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Single-molecule analysis of phospholipid scrambling by TMEM16F

Transmembrane protein 16F (TMEM16F) is a Ca(2+)-dependent phospholipid scramblase that translocates phospholipids bidirectionally between the leaflets of the plasma membrane. Phospholipid scrambling of TMEM16F causes exposure of phosphatidylserine in activated platelets to induce blood clotting and...

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Detalles Bibliográficos
Autores principales: Watanabe, Rikiya, Sakuragi, Takaharu, Noji, Hiroyuki, Nagata, Shigekazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866571/
https://www.ncbi.nlm.nih.gov/pubmed/29507235
http://dx.doi.org/10.1073/pnas.1717956115