BEST1 gene therapy corrects a diffuse retina-wide microdetachment modulated by light exposure

Mutations in the BEST1 gene cause detachment of the retina and degeneration of photoreceptor (PR) cells due to a primary channelopathy in the neighboring retinal pigment epithelium (RPE) cells. The pathophysiology of the interaction between RPE and PR cells preceding the formation of retinal detachm...

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Detalles Bibliográficos
Autores principales: Guziewicz, Karina E., Cideciyan, Artur V., Beltran, William A., Komáromy, András M., Dufour, Valerie L., Swider, Malgorzata, Iwabe, Simone, Sumaroka, Alexander, Kendrick, Brian T., Ruthel, Gordon, Chiodo, Vince A., Héon, Elise, Hauswirth, William W., Jacobson, Samuel G., Aguirre, Gustavo D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866594/
https://www.ncbi.nlm.nih.gov/pubmed/29507198
http://dx.doi.org/10.1073/pnas.1720662115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866594/
https://www.ncbi.nlm.nih.gov/pubmed/29507198
http://dx.doi.org/10.1073/pnas.1720662115

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