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Mutational Profiling of Non-Small-Cell Lung Cancer Resistant to Osimertinib Using Next-Generation Sequencing in Chinese Patients

PURPOSE: To identify the somatic mutated genes for optimal targets of non-small-cell lung cancer after resistance to osimertinib treatment. PATIENTS AND METHODS: Study patients all had advanced lung adenocarcinoma and acquired resistance to osimertinib as a second- or third-line treatment. These pat...

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Detalles Bibliográficos
Autores principales: Nie, Keke, Jiang, Haiping, Zhang, Chunling, Geng, Chuanxin, Xu, Xiajuan, Zhang, Ling, Zhang, Hao, Zhang, Zhongfa, Lan, Ketao, Ji, Youxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866881/
https://www.ncbi.nlm.nih.gov/pubmed/29713646
http://dx.doi.org/10.1155/2018/9010353