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Systematic characterization of pan‐cancer mutation clusters

Cancer genome sequencing has shown that driver genes can often be distinguished not only by the elevated mutation frequency but also by specific nucleotide positions that accumulate changes at a high rate. However, properties associated with a residue's potential to drive tumorigenesis when mut...

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Detalles Bibliográficos
Autores principales: Buljan, Marija, Blattmann, Peter, Aebersold, Ruedi, Boutros, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866917/
https://www.ncbi.nlm.nih.gov/pubmed/29572294
http://dx.doi.org/10.15252/msb.20177974