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Pharmacogenetic Analysis of the Model‐Based Pharmacokinetics of Five Anti‐HIV Drugs: How Does This Influence the Effect of Aging?

Analysis of aging and pharmacogenetics (PGx) on antiretroviral pharmacokinetics (PKs) could inform precision dosing for older human HIV‐infected patients. Seventy‐four participants receiving either atazanavir/ritonavir (ATV/RTV) or efavirenz (EFV) with tenofovir/emtricitabine (TFV/FTC) provided PK a...

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Detalles Bibliográficos
Autores principales: Chen, Jingxian, Akhtari, Farida S., Wagner, Michael J., Suzuki, Oscar, Wiltshire, Tim, Motsinger‐Reif, Alison A., Dumond, Julie B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866997/
https://www.ncbi.nlm.nih.gov/pubmed/29205871
http://dx.doi.org/10.1111/cts.12525