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AZD1208, a pan‐Pim kinase inhibitor, inhibits adipogenesis and induces lipolysis in 3T3‐L1 adipocytes

The proviral integration moloney murine leukaemia virus (Pim) kinases, consisting of Pim‐1, Pim‐2 and Pim‐3, are involved in the control of cell growth, metabolism and differentiation. Pim kinases are emerging as important mediators of adipocyte differentiation. AZD1208 is a pan‐Pim kinase inhibitor...

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Detalles Bibliográficos
Autores principales: Park, Yu‐Kyoung, Obiang‐Obounou, Brice Wilfried, Lee, Kyung‐Bok, Choi, Jong‐Soon, Jang, Byeong‐Churl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867077/
https://www.ncbi.nlm.nih.gov/pubmed/29441719
http://dx.doi.org/10.1111/jcmm.13559