SIRT1/FoxO3 axis alteration leads to aberrant immune responses in bronchial epithelial cells

Inflammation and ageing are intertwined in chronic obstructive pulmonary disease (COPD). The histone deacetylase SIRT1 and the related activation of FoxO3 protect from ageing and regulate inflammation. The role of SIRT1/FoxO3 in COPD is largely unknown. This study evaluated whether cigarette smoke,...

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Detalles Bibliográficos
Autores principales: Di Vincenzo, Serena, Heijink, Irene H., Noordhoek, Jacobien A., Cipollina, Chiara, Siena, Liboria, Bruno, Andreina, Ferraro, Maria, Postma, Dirkje S., Gjomarkaj, Mark, Pace, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867095/
https://www.ncbi.nlm.nih.gov/pubmed/29411515
http://dx.doi.org/10.1111/jcmm.13509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867095/
https://www.ncbi.nlm.nih.gov/pubmed/29411515
http://dx.doi.org/10.1111/jcmm.13509

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