Inducibly decreased MITF levels do not affect proliferation and phenotype switching but reduce differentiation of melanoma cells

Melanoma arises from neural crest‐derived melanocytes which reside mostly in the skin in an adult organism. Epithelial–mesenchymal transition (EMT) is a tumorigenic programme through which cells acquire mesenchymal, more pro‐oncogenic phenotype. The reversible phenotype switching is an event still n...

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Detalles Bibliográficos
Autores principales: Vlčková, Kateřina, Vachtenheim, Jiri, Réda, Jiri, Horák, Pavel, Ondrušová, Lubica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867098/
https://www.ncbi.nlm.nih.gov/pubmed/29369499
http://dx.doi.org/10.1111/jcmm.13506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867098/
https://www.ncbi.nlm.nih.gov/pubmed/29369499
http://dx.doi.org/10.1111/jcmm.13506

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