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Inducibly decreased MITF levels do not affect proliferation and phenotype switching but reduce differentiation of melanoma cells
Melanoma arises from neural crest‐derived melanocytes which reside mostly in the skin in an adult organism. Epithelial–mesenchymal transition (EMT) is a tumorigenic programme through which cells acquire mesenchymal, more pro‐oncogenic phenotype. The reversible phenotype switching is an event still n...
Autores principales: | Vlčková, Kateřina, Vachtenheim, Jiri, Réda, Jiri, Horák, Pavel, Ondrušová, Lubica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867098/ https://www.ncbi.nlm.nih.gov/pubmed/29369499 http://dx.doi.org/10.1111/jcmm.13506 |
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