Synovial fibroblast‐targeting liposomes encapsulating an NF‐κB‐blocking peptide ameliorates zymosan‐induced synovial inflammation

Synovial fibroblasts (SFs) play a crucial role in the inflammatory process of rheumatoid arthritis (RA). The highly activated NF‐κB signal in SFs is responsible for most of the synovial inflammation associated with this disease. In this study, we have developed an SF‐targeting liposomal system that...

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Detalles Bibliográficos
Autores principales: You, Changcheng, Zu, Jianing, Liu, Xiaoqi, Kong, Pengyu, Song, Chengchao, Wei, Rongzhi, Zhou, Changlong, Wang, Yufu, Yan, Jinglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867099/
https://www.ncbi.nlm.nih.gov/pubmed/29383874
http://dx.doi.org/10.1111/jcmm.13549