Norcantharidin, a clinical used chemotherapeutic agent, acts as a powerful inhibitor by interfering with fibrinogen–integrin α(II) (b)β(3) binding in human platelets

During platelet activation, fibrinogen binds to its specific platelet receptor, integrin α(II) (b)β(3), thus completing the final common pathway for platelet aggregation. Norcantharidin (NCTD) is a promising anticancer agent in China from medicinal insect blister beetle. In this study, we provided t...

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Detalles Bibliográficos
Autores principales: Hsia, Chih‐Hsuan, Lu, Wan‐Jung, Lin, Kuan‐Hung, Chou, Duen‐Suey, Geraldine, Pitchairaj, Jayakuma, Thanasekaran, Chang, Nen‐Chung, Sheu, Joen‐Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867116/
https://www.ncbi.nlm.nih.gov/pubmed/29369482
http://dx.doi.org/10.1111/jcmm.13488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867116/
https://www.ncbi.nlm.nih.gov/pubmed/29369482
http://dx.doi.org/10.1111/jcmm.13488

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