SV40 intron, a potent strong intron element that effectively increases transgene expression in transfected Chinese hamster ovary cells

Chinese hamster ovary (CHO) cells have become the most widely utilized mammalian cell line for the production of recombinant proteins. However, the product yield and transgene instability need to be further increased and solved. In this study, we investigated the effect of five different introns on...

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Detalles Bibliográficos
Autores principales: Xu, Dan‐hua, Wang, Xiao‐yin, Jia, Yan‐long, Wang, Tian‐yun, Tian, Zheng‐wei, Feng, Xin, Zhang, Yin‐na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867124/
https://www.ncbi.nlm.nih.gov/pubmed/29441681
http://dx.doi.org/10.1111/jcmm.13504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867124/
https://www.ncbi.nlm.nih.gov/pubmed/29441681
http://dx.doi.org/10.1111/jcmm.13504

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