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SV40 intron, a potent strong intron element that effectively increases transgene expression in transfected Chinese hamster ovary cells
Chinese hamster ovary (CHO) cells have become the most widely utilized mammalian cell line for the production of recombinant proteins. However, the product yield and transgene instability need to be further increased and solved. In this study, we investigated the effect of five different introns on...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867124/ https://www.ncbi.nlm.nih.gov/pubmed/29441681 http://dx.doi.org/10.1111/jcmm.13504 |