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Adoptive transfer of CD3(+) T cells and CD4(+) CD44(high) memory T cells induces autoimmune pancreatitis in MRL/MpJ mice

The immunopathogenesis of autoimmune pancreatitis (AIP) is poorly understood. Here, we have used MRL/MpJ mice, a model of spontaneous AIP, to address the role of cellular autoimmune processes in the initiation and progression of the disease. Therefore, different T cell subpopulations were adoptively...

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Detalles Bibliográficos
Autores principales: Ehlers, Luise, Rohde, Sarah, Ibrahim, Saleh, Jaster, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867153/
https://www.ncbi.nlm.nih.gov/pubmed/29383850
http://dx.doi.org/10.1111/jcmm.13537