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Blockade of cannabinoid 1 receptor improves glucose responsiveness in pancreatic beta cells

Cannabinoid 1 receptors (CB1Rs) are expressed in peripheral tissues, including islets of Langerhans, where their function(s) is under scrutiny. Using mouse β‐cell lines, human islets and CB1R‐null (CB1R (−/−)) mice, we have now investigated the role of CB1Rs in modulating β‐cell function and glucose...

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Detalles Bibliográficos
Autores principales: Shin, Hanho, Han, Ji Hye, Yoon, Juhwan, Sim, Hyo Jung, Park, Tae Joo, Yang, Siyoung, Lee, Eun Kyung, Kulkarni, Rohit N., Egan, Josephine M., Kim, Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867156/
https://www.ncbi.nlm.nih.gov/pubmed/29431265
http://dx.doi.org/10.1111/jcmm.13523