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Histamine Regulates Molecular Clock Oscillations in Human Retinal Pigment Epithelial Cells via H(1) Receptors

Vertebrate eyes are known to contain circadian clocks, but their regulatory mechanisms remain largely unknown. To address this, we used a cell line from human retinal pigment epithelium (hRPE-YC) with stable coexpression of reporters for molecular clock oscillations (Bmal1-luciferase) and intracellu...

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Detalles Bibliográficos
Autores principales: Morioka, Eri, Kanda, Yuzuki, Koizumi, Hayato, Miyamoto, Tsubasa, Ikeda, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867311/
https://www.ncbi.nlm.nih.gov/pubmed/29615980
http://dx.doi.org/10.3389/fendo.2018.00108