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Skeletal Muscle Pyruvate Dehydrogenase Phosphorylation and Lactate Accumulation During Sprint Exercise in Normoxia and Severe Acute Hypoxia: Effects of Antioxidants

Compared to normoxia, during sprint exercise in severe acute hypoxia the glycolytic rate is increased leading to greater lactate accumulation, acidification, and oxidative stress. To determine the role played by pyruvate dehydrogenase (PDH) activation and reactive nitrogen and oxygen species (RNOS)...

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Detalles Bibliográficos
Autores principales: Morales-Alamo, David, Guerra, Borja, Santana, Alfredo, Martin-Rincon, Marcos, Gelabert-Rebato, Miriam, Dorado, Cecilia, Calbet, José A. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867337/
https://www.ncbi.nlm.nih.gov/pubmed/29615918
http://dx.doi.org/10.3389/fphys.2018.00188