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Skeletal Muscle Pyruvate Dehydrogenase Phosphorylation and Lactate Accumulation During Sprint Exercise in Normoxia and Severe Acute Hypoxia: Effects of Antioxidants
Compared to normoxia, during sprint exercise in severe acute hypoxia the glycolytic rate is increased leading to greater lactate accumulation, acidification, and oxidative stress. To determine the role played by pyruvate dehydrogenase (PDH) activation and reactive nitrogen and oxygen species (RNOS)...
Autores principales: | Morales-Alamo, David, Guerra, Borja, Santana, Alfredo, Martin-Rincon, Marcos, Gelabert-Rebato, Miriam, Dorado, Cecilia, Calbet, José A. L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867337/ https://www.ncbi.nlm.nih.gov/pubmed/29615918 http://dx.doi.org/10.3389/fphys.2018.00188 |
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