Stratification of knee osteoarthritis: two major patient subgroups identified by genome-wide expression analysis of articular cartilage

INTRODUCTION: Osteoarthritis (OA) is a heterogeneous and complex disease. We have used a network biology approach based on genome-wide analysis of gene expression in OA knee cartilage to seek evidence for pathogenic mechanisms that may distinguish different patient subgroups. METHODS: Results from R...

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Detalles Bibliográficos
Autores principales: Soul, Jamie, Dunn, Sara L, Anand, Sanjay, Serracino-Inglott, Ferdinand, Schwartz, Jean-Marc, Boot-Handford, Ray P, Hardingham, Tim E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Basic and Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867416/
https://www.ncbi.nlm.nih.gov/pubmed/29273645
http://dx.doi.org/10.1136/annrheumdis-2017-212603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867416/
https://www.ncbi.nlm.nih.gov/pubmed/29273645
http://dx.doi.org/10.1136/annrheumdis-2017-212603

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