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Monocyte alterations in rheumatoid arthritis are dominated by preterm release from bone marrow and prominent triggering in the joint

OBJECTIVE: Rheumatoid arthritis (RA) accompanies infiltration and activation of monocytes in inflamed joints. We investigated dominant alterations of RA monocytes in bone marrow (BM), blood and inflamed joints. METHODS: CD14(+) cells from BM and peripheral blood (PB) of patients with RA and osteoart...

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Detalles Bibliográficos
Autores principales: Smiljanovic, Biljana, Radzikowska, Anna, Kuca-Warnawin, Ewa, Kurowska, Weronika, Grün, Joachim R, Stuhlmüller, Bruno, Bonin, Marc, Schulte-Wrede, Ursula, Sörensen, Till, Kyogoku, Chieko, Bruns, Anne, Hermann, Sandra, Ohrndorf, Sarah, Aupperle, Karlfried, Backhaus, Marina, Burmester, Gerd R, Radbruch, Andreas, Grützkau, Andreas, Maslinski, Wlodzimierz, Häupl, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867420/
https://www.ncbi.nlm.nih.gov/pubmed/29191820
http://dx.doi.org/10.1136/annrheumdis-2017-211649