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Detailed Characterization of T Cell Receptor Repertoires in Multiple Sclerosis Brain Lesions

The antigen-specific activation of pathogenic T cells is considered essential in the initiation and maintenance of multiple sclerosis (MS). The site of activation, the differential involvement of CD4+, and CD8+ T cells, their functional phenotype, and specificity, are important aspects to understand...

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Detalles Bibliográficos
Autores principales: Planas, Raquel, Metz, Imke, Martin, Roland, Sospedra, Mireia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867461/
https://www.ncbi.nlm.nih.gov/pubmed/29616027
http://dx.doi.org/10.3389/fimmu.2018.00509