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Detailed Characterization of T Cell Receptor Repertoires in Multiple Sclerosis Brain Lesions
The antigen-specific activation of pathogenic T cells is considered essential in the initiation and maintenance of multiple sclerosis (MS). The site of activation, the differential involvement of CD4+, and CD8+ T cells, their functional phenotype, and specificity, are important aspects to understand...
Autores principales: | Planas, Raquel, Metz, Imke, Martin, Roland, Sospedra, Mireia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867461/ https://www.ncbi.nlm.nih.gov/pubmed/29616027 http://dx.doi.org/10.3389/fimmu.2018.00509 |
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