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High sensitivity 8-color flow cytometry assay for paroxysmal nocturnal hemoglobinuria granulocyte and monocyte detections

Flow cytometry is the gold standard in diagnosis of paroxysmal nocturnal hemoglobinuria (PNH) by detecting the absence of glycol-phosphatidyl inositol (GPI)-linked protein expression on granulocyte and monocyte surfaces. However, the current assays are not optimized and require improvement, particul...

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Detalles Bibliográficos
Autores principales: Chan, Ray Chun-Fai, Leung, Richard H., Posadas, Albert, Lorey, Thomas S., Shaw, Allison J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867464/
https://www.ncbi.nlm.nih.gov/pubmed/29599976
http://dx.doi.org/10.3892/br.2018.1047