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Age-Related Changes in the Behavior of Apolipoprotein E Knockout Mice

The knockout mouse model, B6.129P2-Apoe(tm1Unc) is homozygotic for the Apolipoprotein E (ApoE) deletion; thus, it is capable of developing hyperlipidemia and atherosclerosis but ApoE is also a lipid-transport protein abundantly expressed in most neurons in the central nervous system, so these animal...

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Detalles Bibliográficos
Autores principales: Fuentes, Dasha, Fernández, Nidia, García, Yenela, García, Teidy, Morales, Ana Ruth, Menéndez, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867486/
https://www.ncbi.nlm.nih.gov/pubmed/29510495
http://dx.doi.org/10.3390/bs8030033