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Effect of curcumin on vascular endothelial growth factor in hypoxic HepG2 cells via the insulin-like growth factor 1 receptor signaling pathway

To investigate the anti-angiogenic effect and underlying molecular mechanisms of curcumin on HepG2 cells under hypoxic conditions, insulin-like growth factor 1 receptor (IGF-1R) knockout HepG2 cells were constructed using a clustered regularly interspaced short palindromic repeats/Cas9 genome-editin...

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Detalles Bibliográficos
Autores principales: Chen, Yihui, Zhong, Wei, Chen, Baohua, Yang, Chuanyu, Zhou, Song, Liu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867490/
https://www.ncbi.nlm.nih.gov/pubmed/29599831
http://dx.doi.org/10.3892/etm.2018.5783