Attempted replication of SNPs in RANKL and OPG with musculoskeletal adverse events during aromatase inhibitor treatment for breast cancer

Aromatase inhibitor (AI) therapy is highly efficacious in the treatment of estrogen receptor-positive breast cancer; however, in a subset of patients AI use is discontinued due to drug-induced musculoskeletal adverse events (MS-AE). Several studies have investigated the role of germline single nucle...

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Detalles Bibliográficos
Autores principales: Dempsey, Jacqueline M., Xi, Jingyue, Henry, N. Lynn, Rae, James M., Hertz, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2018
Materias:
PG SNPs
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867615/
https://www.ncbi.nlm.nih.gov/pubmed/29212847
http://dx.doi.org/10.1152/physiolgenomics.00085.2017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867615/
https://www.ncbi.nlm.nih.gov/pubmed/29212847
http://dx.doi.org/10.1152/physiolgenomics.00085.2017

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