Function-Oriented Synthesis of Marine Phidianidine Derivatives as Potential PTP1B Inhibitors with Specific Selectivity

Phidianidines A and B are two novel marine indole alkaloids bearing an uncommon 1,2,4-oxadiazole ring and exhibiting various biological activities. Our previous research showed that the synthesized phidianidine analogs had the potential to inhibit the activity of protein tyrosine phosphatase 1B (PTP...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Jin, Chen, Yu, Li, Jing-Ya, Luo, Cheng, Li, Jia, Chen, Kai-Xian, Li, Xu-Wen, Guo, Yue-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867641/
https://www.ncbi.nlm.nih.gov/pubmed/29558377
http://dx.doi.org/10.3390/md16030097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867641/
https://www.ncbi.nlm.nih.gov/pubmed/29558377
http://dx.doi.org/10.3390/md16030097

Ejemplares similares