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Function-Oriented Synthesis of Marine Phidianidine Derivatives as Potential PTP1B Inhibitors with Specific Selectivity

Phidianidines A and B are two novel marine indole alkaloids bearing an uncommon 1,2,4-oxadiazole ring and exhibiting various biological activities. Our previous research showed that the synthesized phidianidine analogs had the potential to inhibit the activity of protein tyrosine phosphatase 1B (PTP...

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Detalles Bibliográficos
Autores principales:	Liu, Jin, Chen, Yu, Li, Jing-Ya, Luo, Cheng, Li, Jia, Chen, Kai-Xian, Li, Xu-Wen, Guo, Yue-Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867641/ https://www.ncbi.nlm.nih.gov/pubmed/29558377 http://dx.doi.org/10.3390/md16030097

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