Deep-Coverage MPS Analysis of Heteroplasmic Variants within the mtGenome Allows for Frequent Differentiation of Maternal Relatives

Distinguishing between maternal relatives through mitochondrial (mt) DNA sequence analysis has been a longstanding desire of the forensic community. Using a deep-coverage, massively parallel sequencing (DCMPS) approach, we studied the pattern of mtDNA heteroplasmy across the mtgenomes of 39 mother-c...

Descripción completa

Detalles Bibliográficos
Autores principales: Holland, Mitchell M., Makova, Kateryna D., McElhoe, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867845/
https://www.ncbi.nlm.nih.gov/pubmed/29495418
http://dx.doi.org/10.3390/genes9030124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867845/
https://www.ncbi.nlm.nih.gov/pubmed/29495418
http://dx.doi.org/10.3390/genes9030124

Ejemplares similares