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Resolving the Enigma of the Clonal Expansion of mtDNA Deletions

Mitochondria are cell organelles that are special since they contain their own genetic material in the form of mitochondrial DNA (mtDNA). Damage and mutations of mtDNA are not only involved in several inherited human diseases but are also widely thought to play an important role during aging. In bot...

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Detalles Bibliográficos
Autores principales: Kowald, Axel, Kirkwood, Thomas B.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867847/
https://www.ncbi.nlm.nih.gov/pubmed/29495484
http://dx.doi.org/10.3390/genes9030126