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Characterizing the DNA Methyltransferases of Haloferax volcanii via Bioinformatics, Gene Deletion, and SMRT Sequencing

DNA methyltransferases (MTases), which catalyze the methylation of adenine and cytosine bases in DNA, can occur in bacteria and archaea alongside cognate restriction endonucleases (REases) in restriction-modification (RM) systems or independently as orphan MTases. Although DNA methylation and MTases...

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Detalles Bibliográficos
Autores principales: Ouellette, Matthew, Gogarten, J. Peter, Lajoie, Jessica, Makkay, Andrea M., Papke, R. Thane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867850/
https://www.ncbi.nlm.nih.gov/pubmed/29495512
http://dx.doi.org/10.3390/genes9030129