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Caenorhabditis elegans BRICHOS Domain–Containing Protein C09F5.1 Maintains Thermotolerance and Decreases Cytotoxicity of Aβ(42) by Activating the UPR

Caenorhabditis elegans C09F5.1 is a nematode-specific gene that encodes a type II transmembrane protein containing the BRICHOS domain. The gene was isolated as a heat-sensitive mutant, but the function of the protein remained unclear. We examined the expression pattern and subcellular localization o...

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Detalles Bibliográficos
Autores principales: Song, Myungchul, Song, Kyunghee, Kim, Sunghee, Lee, Jinyoung, Hwang, Sueyun, Han, Chingtack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867881/
https://www.ncbi.nlm.nih.gov/pubmed/29534049
http://dx.doi.org/10.3390/genes9030160