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Astrocytic Interleukin-15 Reduces Pathology of Neuromyelitis Optica in Mice

Astrocyte loss induced by neuromyelitis optica (NMO)-IgG and complement-dependent cytotoxicity (CDC) is the hallmark of NMO pathology. The survival of astrocytes is thought to reflect astrocyte exposure to environmental factors in the CNS and the response of astrocytes to these factors. However, sti...

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Detalles Bibliográficos
Autores principales: Li, Zhiguo, Han, Jinrui, Ren, Honglei, Ma, Cun-Gen, Shi, Fu-Dong, Liu, Qiang, Li, Minshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867910/
https://www.ncbi.nlm.nih.gov/pubmed/29616032
http://dx.doi.org/10.3389/fimmu.2018.00523