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MiR-215-5p is a tumor suppressor in colorectal cancer targeting EGFR ligand epiregulin and its transcriptional inducer HOXB9

Growing evidence suggests that microRNAs are involved in the development and progression of colorectal cancer (CRC). In the present study, deregulation and functioning of tumor-suppressive miR-215-5p was evaluated in CRC. In total, 448 tumor tissues and 325 paired adjacent healthy tissues collected...

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Detalles Bibliográficos
Autores principales: Vychytilova-Faltejskova, Petra, Merhautova, Jana, Machackova, Tana, Gutierrez-Garcia, Irene, Garcia-Solano, José, Radova, Lenka, Brchnelova, Dominika, Slaba, Katerina, Svoboda, Marek, Halamkova, Jana, Demlova, Regina, Kiss, Igor, Vyzula, Rostislav, Conesa-Zamora, Pablo, Slaby, Ondrej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868056/
https://www.ncbi.nlm.nih.gov/pubmed/29199273
http://dx.doi.org/10.1038/s41389-017-0006-6