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Inhibition of PI3K/AKT Signaling Pathway Radiosensitizes Pancreatic Cancer Cells with ARID1A Deficiency in Vitro

Pancreatic cancer is among the most aggressive human cancers, and is resistant to regular chemotherapy and radiotherapy. The AT-rich interactive domain containing protein 1A (ARID1A) gene, a crucial chromatin remodeling gene, mutates frequently in a broad spectrum of cancers, including pancreatic ca...

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Detalles Bibliográficos
Autores principales: Yang, Lin, Yang, Guanghai, Ding, Yingjun, Dai, Yuhong, Xu, Sanpeng, Guo, Qiuyun, Xie, Aini, Hu, Guangyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868153/
https://www.ncbi.nlm.nih.gov/pubmed/29581767
http://dx.doi.org/10.7150/jca.21306