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Autophagy Inhibition Stimulates Apoptosis in Oesophageal Squamous Cell Carcinoma Treated with Fasudil

Fasudil has been proven to be a promising chemotherapeutic drug for various malignancies. However, the potential anticancer effects of fasudil in oesophageal squamous cell carcinoma (ESCC) remain to be established. We confirmed the RhoA activity is inhibited by fasudil in ESCC cells. Then measured t...

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Detalles Bibliográficos
Autores principales: Xie, Fa-Jun, Zheng, Qiu-Qing, Qin, Jing, Zhang, Ling-Ling, Han, Na, Mao, Wei-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868172/
https://www.ncbi.nlm.nih.gov/pubmed/29581784
http://dx.doi.org/10.7150/jca.23388