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A Meta-Analysis: Methylenetetrahydrofolate Reductase C677T Polymorphism in Gastric Cancer Patients Treated with 5-Fu Based Chemotherapy Predicts Serious Hematologic Toxicity but Not Prognosis

5-fluorouracil (5-Fu) metabolism associated enzyme, methylenetetrahydrofolate reductase (MTHFR)'s polymorphism C677T can affect enzyme activity and a series of studies have been performed to examine the association of this MTHFR polymorphism with the clinical outcomes of gastric cancer (GC) pat...

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Detalles Bibliográficos
Autores principales: Tang, Cheng, Yu, Shan, Jiang, Huiqin, Li, Wei, Xu, Xiaojing, Cheng, Xi, Peng, Ke, Chen, Erbao, Cui, Yuehong, Liu, Tianshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868173/
https://www.ncbi.nlm.nih.gov/pubmed/29581785
http://dx.doi.org/10.7150/jca.23391